PGD probe 9 vs. 12

Hi there,

Funny enough Dr Frederick recommends just 5 probe PGD. She says with the 9 and 12 probe there are too many errors, lots of women have no embryos to transfer, yet some of them may have really been normal embryos after all.

So I will stick to 5 probe again for next time.

sarita 

Has anyone heard that if you donate your eggs you can do MS for practily free? I read an article about it not long ago but it was written by a group against MS.

sorry i'm asking so many questions i'm sure it's getting annoying.

wanting pink:

Hi TJ,

 Do you know which probe was used on the cycle you did PGD?

Dear wanting pink:

I did what GIVF calls the "mini aneuploidy" panel with gender selection which checks for chromosomes 13, 18, 21 as well as X & Y for gender.    I actually found talking with the genetics counselor who had extensive knowledge about PGD lab techniques and issues very helpful.  Usually the genetics counselors that work at IVF clinics have a masters degree in genetic counseling and the one I dealt with at GIVF seemed to be very up to speed on current issues with PGD.    Also, it was after a lengthy meeting with the genetic counselor for almost an hour that we determined I was a good canidate for the "mini aneuploidy" given my lack of miscarriage issues, genetic abnomalites, etc... So, with her input and the discussion we were able to decide with confidence to do the mini panel rather than at wider panel like the 12 panel screening.  Also, I was given at my ET a copy of the official PGD biopsy report.  TJ

 Quote from ababygirl4me:

"i've read that many times there is a 3 day transfer when just doing ivf, but allowing it to grow a few more days gives a chance to weed out those embies that wouldnt be fit enough to transfer by day 5, upping the pregnancy rate."  

Ababygirl4me:    Actually, one of the other contributing reasons why I did not do PGD on the 2nd cycle is because a lot of what I was reading and researching was showing LOWER pregnancy rates with PGD not necessarily higher.  I just wanted to add that for some people PGD may increase chance for pregnacy and for others the embryo may be weakened after PGD even though it survives the biopsy and goes to transfer.   In my opinion, the embryo may be "compromised" in some way which reduce the likelihood of pregnancy especially if the RE experience or skills are not excellent or the embryo simply did not like being manipulated.  Just my thoughts. TJ

Below is link that mentions lower pregnancy rates with PGD not higher:  This link discusses two studies one small and one larger that showed lower pregnancy rates for pgd cycles. 

http://www.advancedfertility.com/preimplantation%20genetic%20diagnosis.htm

My head is literally spinning with new information!! Ahhhh save me!

KD

The link to that board is www.ivfconnections.com

 you need to go to IVF and then special procedures - PGD is at the bottom I think

I just wanted to add that IF my PGD cycle had resulted in a BFP I imagine that I would of been the biggest fan ever for PGD and even though my PGD cycle did not end up successful I still think the technology and the 100% gender results is the way to go IF you cannot accept the possibility of having an opposite gender.   My DD journey started with IUI/MS so I was definitely willing to accept an opposite.  However, for me there was this GRAY area where I evolved after the 3 BFNs and being pregnant as well as getting my DD started to equal out after I started to feel like I was infertile or a failure.  So my emotions really started to control my decision making at times and I just really felt that after the PGD BFN that a different approach had to be taken.  Of course, my DH kept reminding me that I was willing to do IUI with just MS so WHY would I not take the same gamble with IVF and do just MS.   My best advice is give yourself the flexibility to change your mind.  I am a very intuitive person and go with my gut a lot thankfully to my benefit.  However, each person comes to these decisions in complex ways and alot will depend on how the cycle goes and your success.  In my mind I was dead set on PGD and admire the technology but in my heart after the failure I just had to try a different approach.  I wished that PGD cycle was successful for me given I paid $5,000 to do it. It is healthy to keep an OPEN MIND and ultimately do what you will be at peace with whether you get a BFP or BFN.  I do not regret doing PGD and had my IVF/MS cycle not worked my plan C was to do just IVF/PGD and forget MS because then I would of been thinking "oh it was the darn MS that was messing with my embryos" for the last cycle.   AND had that not worked I was going back to give IUI/MS two more attempts.     TJ

Jodi,

 I will be following your cycle closely! I am hoping for the best for you!! I'll be in your shoes come Oct. with the PGD/IVF!

KD