Transfer 1 or 2?? How to know??

I need some advice on transferring one or two embryos. It's been a roller-coaster journey so far. My DH and I have to wonderful boys and we both feel that a daughter (or two) would complete our family. I had severe gender disappointment and have struggled since my last son was born 5 years ago. We started our journey last month with surprising retrieval of 51 eggs!! Was suppose to do a fresh 3 day transfer however because I got very sick with Hyperstimulation the transfer was cancelled. I was glad for the fact because I felt terrible and know that hyperstimulation when pregnant can be worse and lasting many weeks. We were disappointed though to have to wait longer for the transfer. The exciting part was that we had 51 eggs and thought we were sure to get more than plenty female embryos after PGD testing. Well we were very disappointed to get the news that at day 5 only 4 embryos were strong enough to survive. I prepared myself that all four could be male and if that was the case we had done what we could. With limited finances and me not physically up for another treatment we decided it was a one shot deal for us. Friday the wonderful PGD test results came in that 2 are female, 1 male and 1 undetermined would need a rebyopsy. My hope is back!! Now for the big decision of transferring one or two embryos. Both are of good quality but my odds of having twins if transferring 2 is 2/3 to be twins. I'm not against twins completely but our lives financially and otherwise would be turned upside down. Would my boys be OK with twins getting all the attention forever?? Could I do it?? So I don't want to start getting picky because I feel very thankful thus far but do we transfer one at a time or both together. I'm on the fence: first because what if meds don't get me completely ready and if I transfer two and neither work...but then again what if we transfer one and the other doesn't thaw well or we loose it for some reason (even though the embryologist says there is only a 2% change of this). I don't want to put all my eggs in one basket but also don't want to loose one in error and be without any. Any advice or experiences to share would be much appreciated. Transfer date isn't until end of May so I have some time even though the waiting and endless thinking about it is driving me nuts. Thank you in advance!

 The day of my ET, I had 3 healthy female embryos.  I wanted a daughter and almost transferred all three embryos but I didn't want to risk having triplets (LOL).  It was a hard decision because I was afraid the embryo I didn't transfer would have been the one.  In the end, we transferred two healthy female embryos and had the surprise of a life when we had our first ultrasound and saw three little babies.  We are now the proud parents of identical twins with a fraternal triplet.  I can honestly say, I wouldn't change a thing.  Multiples are a lot of work but they are worth it!  Financially, it was difficult at first but we figured it out.  Good luck with your decision.  

Sunshine, I know exactly how you feel. I went to Genesis last year and was adamant the whole time we would only put 1 back. I really didn't want twins. The dr then gently persuaded me to put 2 back and freeze one. He said the actual odds of me giving birth to live twins was less than 20%. I was so sure I would be a OHW like everyone on here I guess, it was shocking when I got my BFN. I STILL don't know if I did the right thing. What I do know is that if i'd only put back one and got my BFN (which I obviously would have) I'm sure I would have blamed myself for not listening to the dr. It seems to me that your body is either ready to hang on to those babies or it just isn't. I've been on the other board and LoTS and lots of women are getting pg with frozen tranfers. Most of the ladies who cycled at a similar time to me either got a BFN or pg with twins!! I would love to know the real stats of how many people put 2 back and only get pg with one. I'm going back to Genesis in May and am still petrified on how many to put back. I know he will try to convince me to put back 2 again. i probably will put back 2 as it's such a rollercoaster to go through to get a BFN but the idea of waiting 12 weeks to find out whether its twins also petrifies me. I'm not sure how my husband would cope - he doesn't really want any more kids but does want to see me happy so is adamant we'll keep trying til I get my DD. I know that if all else fails I will return for a FET. I def still have one in the freezer from last time and hopefully i can add to that this cycle. Good luck but I'm all for frozen transfers. I think I'd try with just the one and then if that fails I'd defrost and go back for a FET. I think your body may cope better without all the meds. You just need to be sure in your mind that what you decide is the right decision. please don't spend forever thinking what if... Good luck with everything xx

I know exactly how you feel.  I was in a similar situation with my first cycle.  I did toss up whether or not to transfer the 2 embies we had, but neither of us wanted twins and I felt better knowing I'd have a back up.  I transferred the first fresh 1 and it was a bfn.  I was sooooo disappointed and thought that maybe if I had transferred the 2 I'd be pregnant.  But then, after more thinking I realised that maybe it was my body and not necessarily the embryo, everything needs to be perfect.  So we went on to our FET and my embie didn't survive the thaw, this obviously made me even more upset.  But, to be honest, looking back now, I really don't think that it would have if I transferred the 2 at the beginning because I was so stressed that cycle and very anxiou, and I did feel VERY relaxed on the FET cycle and felt confident that if the embie thawed I'd have a good shot because I was in a better mind set and not so anxious.  I guess to answer your question, because your embies are already frozen, it really makes no difference transferreing 1 or 2, either way they still have to survive the thaw.  I would probably do 1 at a time so that if things aren't perfect in the first cycle the doc can correct it in the next one.  Good luck

As someone who's had a bunch of hi-tech disappointments, I can say for a fact that I'd rather risk twins than have none at all. Don't be so quick  to assume that you will get pregnant with a single embryo the very first time around.

I don't know what kind of PGD you did, but unless it was 24 chrom testing, there's a 40-60% chance your "normal" embryos are really abnormal with the fewer probes. I would transfer both (one might not even survive the thaw so you'd end up with SET anyways).

I hope that helps.

Good luck!

I agree with Jackie's Hope, just because you transfer two embies doesn't mean they will both take, last fall we were lucky enough to have two female embryo's to transfer, we were thrilled and hoped that they would both make it, but if not then at least one would. Neither stuck, 2nd cycle was cxld due to no response to meds. Third cycle out of 7 eggs retrieved, only 1 made it and she was our girl, but sadly she never grew. I just found out last Monday, no heartbeat. So even if you are fortunate enough to have two female embryo's left, you may get nothing. I go with two over one anyday, just to up my odds. It really is alot harder than it seems.

I have put back 7 female embryos total and no baby.  I swear I would put back 5 at this point...

I would not put back less than 2 if I had the choice..

I personally want twins, but we have only had 2 each time to put back. First time 1 took, second time, both, but all ended in m/c. Depending on your age, 2 may be best. 51 is awesome! How did you get so many? I would love at least 15!

hi sunshine for me, have you decided what you are going to do yet?  I started my stims on Sat, fly out to Genesis Cyprus this Sunday with family. Collection is due about 24th May and I still don't know whether to put back one or 2.  I just feel like it will either not work at all or I'll get twins (which I know is some people's dream but it wouldn't be my ideal situation, I'm like you with 2 boys already and don't want to spread myself too thin).  Do you have any idea if hyperstimulation is a one-off thing, or if you have it once are you likely to get it each time if on same medication?  I got a mild form of it last time (although still had ET - sure that was partly to blame for my BFN) and am scared I'll get it again.  Not sure what to do to prevent/help the situation either!!  Good luck with whatever you decide xx